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网站首页>产品展示 > 衍生化/食品/药品等标准品 > OLchem植物生长素 > olchemim Cyclin-dependent kinase inhibitors
olchemim Cyclin-dependent kinase inhibitors

发布时间:2017-03-30

产品型号:

公司地址:广州市天河区天河北路侨林街47号中旅商务大厦东塔20D

产品价格:来电咨询

产品详情在线留言

Molecules that play key roles in controlling cell-cycle progression are the cyclin-dependent kinase (CDK). Research focused on the primary mechanism of cytokinin action in cell division cycle has showed that natural cytokinins are rather non-specific inhibitors of various kinases. Surprisingly, among cytokinin derivatives, a BAP derivative named olomoucin (OC), which specifically inhibits some CDKs at micromolar concentration.

OLOMOUCINE [6-benzylamino-2-(2-hydroxyethylamino)-9-methylpurine]

MW 298.35, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: 101622-51-9; C15H18N6O
OLOMOUCINE
008 021110mg
008 021220mg
008 0213100mg
008 02141mg

BOHEMINE [6-benzylamino-2-(3-hydroxypropylamino)-9-isopropylpurine]

MW 340.43, crystalline, purity > 98% (HPLC)
IC50 value for CDK1: 1 µM
S:26, 36; CAS: 189232-42-6; C18H24N6O
BOHEMINE
008 07715mg
008 077210mg
008 077350mg

2-HYDROXYBOHEMINE (HOB) [6-(2-hydroxybenzylamino)-2-(3-hydroxypropylamino)-9-isopropylpurine]

MW 356.43, crystalline, purity > 98% (HPLC)
IC50 value for CDK1: 0.1 µM
S:26, 36; CAS: 471270-60-7; C18H24N6O2
2-HYDROXYBOHEMINE (HOB)
008 59315mg
008 593210mg
008 593350mg

ISOPROPYL-OLOMOUCINE [6-benzylamino-2-(2-hydroxyethylamino)-9-isopropylpurine]

MW 326.40, crystalline, purity > 98% (HPLC)
IC50 value for CDK1: 2 µM
S:26, 36; CAS: 158982-15-1; C17H22N6O
ISOPROPYL-OLOMOUCINE
008 07815mg
008 078210mg
008 078350mg

ISO-OLOMOUCINE [6-benzylamino-2-(2-hydroxyethylamino)-7-methylpurine]

MW 298.35, crystalline, purity > 98% (HPLC)
Inactive 7-isomer of olomoucine.
IC50 value for CDK1: 200 µM
S:26, 36; CAS: 101622-50-8; C15H18N6O
ISO-OLOMOUCINE
008 07915mg
008 079210mg
008 079350mg

OLOMOUCINE II [6-(2-hydroxybenzylamino)-2(R)-[1-(hydroxymethyl)propyl]amino-9-isopropylpurine]

MW 370.46, crystalline, purity > 98% (HPLC)
IC50 value for CDK1: 0.02 µM
S:26, 36; CAS: 500735-47-7; C19H26N6O2
OLOMOUCINE II
008 52615mg
008 526210mg
008 526350mg

RS-ROSCOVITINE [6-benzylamino-[2-(1(RS)-(hydroxymethyl)propyl]amino-9-isopropylpurine]

MW 354.45, crystalline, purity > 98% (HPLC)
IC50 value for CDK1: 0.45 µM
S:26, 36; CAS: 186692-44-4; C19H26N6O
RS-ROSCOVITINE
008 03615mg
008 036210mg
008 036350mg

R-ROSCOVITINE 6-benzylamino-2-[1(R)-(hydroxymethyl)propyl]amino-9-isopropylpurine]

MW 354.45, crystalline, purity > 98% (HPLC)
IC50 value for CDK1: 0.2 µM
S:26, 36; CAS: 186692-46-6; C19H26N6O
R-ROSCOVITINE
008 57415mg
008 574210mg
008 574350mg

S-ROSCOVITINE [6-benzylamino-2-[1(S)-(hydroxymethyl)propyl]amino-9-isopropylpurine]

MW 354.45, crystalline, purity > 98% (HPLC)
IC50 value for CDK1: 0.6 µM
S:26, 36; CAS: 186692-45-5; C19H26N6O
S-ROSCOVITINE
008 57515mg
008 575210mg
008 575350mg

PURVALANOL A [6-(3-chlorophenyl)amino-2-[1(R)-(hydroxymethyl)-2-(methyl)propyl]amino-9-isopropylpurine]

MW 388.90, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: 212844-53-6; C19H25ClN6O
PURVALANOL A
008 08515mg
008 085210mg
008 085350mg

AMINOPURVALANOL (APURV) [(R)-2-[6-(3-amino-5-chlorophenylamino)-9-isopropyl-9H-purin-2-ylamino]-3-methyl-butan-1-ol]

MW 403.91, crystalline, purity > 98% (HPLC)
R:22, S:22, 24/25; CAS: 220792-57-4; C19H26ClN7O
AMINOPURVALANOL (APURV)
008 59515mg
008 595210mg
008 595325mg

MYOSEVERIN [9-isopropyl-2,6-bis(4-methoxybenzylamino)purine]

MW 432.53, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: 267402-71-1; C24H28N6O2
MYOSEVERIN
008 08615mg
008 086210mg
008 086350mg

2-CHLORO-6-BENZYLAMINO-9-ISOPROPYLPURINE

MW 301.78, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: 186692-41-1; C15H16ClN5
2-CHLORO-6-BENZYLAMINO-9-ISOPROPYLPURINE
008 527150mg
008 5272100mg
008 5273250mg
008 52741g

2-CHLORO-6-BENZYLAMINO-7-METHYLPURINE

MW 273.73, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: 101622-52-0; C13H12ClN5
2-CHLORO-6-BENZYLAMINO-7-METHYLPURINE
008 528110mg
008 528250mg
008 5283100mg

2-CHLORO-6-BENZYLAMINO-9-METHYLPURINE

MW 273.73, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: 101622-53-1; C13H12ClN5
2-CHLORO-6-BENZYLAMINO-9-METHYLPURINE
008 529150mg
008 5292100mg
008 5293250mg
008 52941g

2-CHLORO-6-(ISOPENT-2-ENYLAMINO)-9-METHYLPURINE

MW 251.72, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: 189232-32-4; C11H14ClN5
2-CHLORO-6-(ISOPENT-2-ENYLAMINO)-9-METHYLPURINE
008 530150mg
008 5302100mg
008 5303250mg
008 53041g

CVT 313

MW 400.48, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: 199986-75-9; C20H28N6O3
CVT 313
008 57615mg
008 576210mg
008 576350mg

NG 38 [2-(1-piperenidinyl)-6-(3-nethoxybenzylamino)-9-isopropylpurine]

MW 380.50, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: NONE; C21H28N6O
NG 38
008 59115mg
008 591210mg
008 591350mg

2-(2-HYDROXYETHYLAMINO)-6-(ISOPENT-2-ENYLAMINO)-9-METHYLPURINE

MW 276.34, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: 158982-16-2; C13H20N6O
2-(2-HYDROXYETHYLAMINO)-6-(ISOPENT-2-ENYLAMINO)-9-METHYLPURINE
008 53115mg
008 531210mg
008 531350mg

INDIRUBIN [3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one]

MW 260.27, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: 479-41-4; C16H10N2O2
IC50 value for CDK1: 10 µM
INDIRUBIN
008 58315mg
008 583210mg
008 583350mg

INDIRUBIN-5’-SULPHONIC ACID [3,2'-dioxo-1,3,1',2'-tetrahydro-[2,3']biindolylidene-5'-sulfonic acid]

MW 342.33, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: 864131-82-8; C16H10N2O5S
IC50 value for CDK1: 0.055 µM
INDIRUBIN-5’-SULPHONIC ACID
008 58415mg
008 584210mg
008 584350mg

INDIRUBIN-3’-MONOOXIME [1H,1'H-[2,3']bisindolylidene-3,2'-dione 3-oxime]

MW 277.28, crystalline, purity > 98% (HPLC)
S:26, 36; CAS: 160807-49-8; C16H11N3O2
IC50 value for CDK1: 0.18 µM
INDIRUBIN-3’-MONOOXIME
008 58515mg
008 585210mg
008 585350mg
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